A form of Parkinson's disease caused by mutations in a gene known as PINK1 has long been labeled rare. But our research shows it's anything but—at least for some populations.

Misbehaving T cells light up long before Parkinson’s symptoms show, zeroing in on vulnerable brain proteins. Their early ...

Scientists have finally pinned down a protein that’s largely responsible for Parkinson’s disease. Known as PINK1, the protein has been linked to the disease for decades but its structure and ...

Restoring the function of pathogenic PINK1 mutations found in Parkinson’s patients with small molecule drugs, is a paradigm shift in Parkinson’s disease.

Researchers say structure reveals many new ways to change PINK1, essentially switching it on, which will be "life-changing" for people with Parkinson’s disease.

Progenra Inc. reports that it has discovered a new class of small-molecule PINK1 activators that restore function in mutant forms of the PINK1 kinase, a key mitochondrial regulator whose dysfunction ...

A progressive neurological disorder affecting 10 million people globally, Parkinson’s can cause disruptive symptoms such as ...

A new study reveals that T cells mistakenly attack brain cells expressing PINK1, contributing to Parkinson’s disease. The research also highlights a striking sex difference, with men showing a sixfold ...

Parkinson's disease occurs when brain cells that produce an important hormone called dopamine begin to die off or become ...

Israeli researchers said Friday they have developed a simple, "revolutionary" blood test that for the first time would allow doctors to detect the onset of Parkinson's disease in its very earliest ...