Background Idiopathic pulmonary fibrosis (IPF) is a progressive disease of lung parenchymal scarring that is triggered by ...

A recent study published in Frontiers in Immunology discussed how injury and abnormal repair of the airway epithelium drive chronic obstructive pulmonary disease (COPD) and asthma. Study ...

The researchers found that "ever" smokers, in contrast to "never" smokers, had upregulated ANO1 expression in airway epithelial cells. Similarly, airway epithelial cells in a bronchoalveolar ...

A fundamental challenge for cystic fibrosis (CF) gene therapy is ensuring sufficient transduction of airway epithelial cells to achieve therapeutic correction. Vehicles such as lysophosphatidylcholine ...

Airway epithelial cells act as a physical barrier against environmental toxins and injury, and modulate inflammation and the immune response. As such, maintenance of their integrity is critical.

This study introduces a novel mechanism to explain how increased VPD can affect airway epithelial cells. Researchers observed how airway mucus, a dilute hydrogel composed of salts, globular ...

The research, led by Veena Antony, M.D., a professor in the UAB Department of Medicine, focuses on microRNA-381, and the expression of a chloride channel gene called ANO1 in lung tissue samples and ...