Aminoglycosides are a class of antibiotics used to treat serious infections caused by bacteria that are difficult to treat. Aminoglycosides are called bactericidal antibiotics because they kill ...

NEW ORLEANS, LA—Extended-interval aminoglycoside dosing “appears of be safe in pediatric patients,” a retrospective study presented at IDWeek has found.—Extended-interval aminoglycoside dosing ...

Translation occurs at a reduced rate in bacterial persisters 2,8, indicating that they should be susceptible to aminoglycosides, which are ribosome-targeting bactericidal antibiotics 9,10,11,12,13 ...

Gentamicin treatment caused a significant reduction in basal potential difference in the 19 patients carrying stop mutations (from –45±8 to –34±11 mV, P=0.005) and a significant response to ...

An expert briefly describes the study ‘Single Dose Aminoglycosides versus Carbapenems for the Treatment of Uncomplicated Urinary Tract Infections Caused by Extended-Spectrum β-lactamase ...

Two primary resistance mechanisms—aminoglycoside enzymatic modification and 16S rRNA methylation—were assessed, and the prevalence of the corresponding ARGs was described.

Background: Empiric dosing of gentamicin has not been evaluated in critically ill neonates with unrepaired congenital heart disease (CHD). Many factors may alter gentamicin pharmacokinetics in ...

Side effects. Aminoglycosides can override the stop signal on their own, but this requires a very high dose, causing many side effects. As mefloquine boosts the efficiency of aminoglycosides, the ...

Researchers at the University of Kentucky's College of Medicine have found that a class of antibiotics called aminoglycosides could be a promising treatment for frontotemporal dementia.

A total of 195 patients completed the study. They received 80 to 160 mg of gentamicin twice daily by intravenous infusion (generally for 5 to 7 days) and were randomly assigned to receive 14 days ...

Side effects. Aminoglycosides can override the stop signal on their own, but this requires a very high dose, causing many side effects. As mefloquine boosts the efficiency of aminoglycosides, the ...