TMC207 is a first-in-class anti-TB diarylquinoline (also named R207910 or the 'J' compound) with activity against drug-sensitive and drug-resistant TB. TMC207 inhibits the proton pump of ...

Researchers have identified a compound that can fight against all the strains of the drug-resistant Mycobacterium ...

Currently, several states have outbreaks. In Kansas City, where cases have increased 148%, two deaths have been reported ...

The bacteria that cause tuberculosis (TB) may have an "on-off switch" that lets them pause and restart growth, according to a ...

Anti-tuberculosis drug-induced acute kidney injury is not rare in an aging population. It usually develops within two months of treatment and resolves within three months after onset. Although ...

ICMR soon to begin landmark TB study testing high-dose rifampicin regimens: Shardul Nautiyal, Mumbai Tuesday, May 13, 2025, ...

MDR-TB is a particularly complicated form of TB, resisting at least two of the standard four-drug, anti-TB drugs. Inadequately treated patients are likely to increase selective pressure ...

Most bacteria have few, if any, P450s but we discovered that the TB bacterium has 20 different types." Even more exciting for the team was the knowledge that existing anti-fungal drugs already target ...