Researchers show that analyzing the 3D shapes of antibodies, not just their genetic sequences, can better group functionally ...

Vertebrates with a defined immune system, such as humans, have an immune response consisting of an innate and adaptive response, also known as a specific response. The specific response is ...

How the CDR loop that houses most of the different contacts might relate to oligomer properties is unknown, as is whether the oligomer-binding antibody 12A11 can prevent neuronal toxicity or loss. A ...

In the September 25 PNAS online, researchers led by Chris Dealwis at the University of Tennessee in Knoxville published the first crystal structure of a monoclonal antibody to the amyloid-β (Aβ) ...

Researchers have now visualized the molecular structure of the LAG3 protein. They describe the crystal structure of ... This anti-LAG3 antibody, called relatlimab, was administered in combination ...

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