The medications discussed in this article have very different mechanisms of action, but all were designed with one primary goal: to alter the balance between procoagulant and anticoagulant ...

Though both types of medications serve similar purposes, they work through different mechanisms and have distinct uses.

Despite advances in anticoagulant therapies, bleeding remains a critical concern.Traditionally, the definition of major ...

The need for physicians to walk a tightrope between preventing thromboembolic events and causing major bleeds is due to DOACs’ mechanism of action. All existing anticoagulants act on a pathway ...