For patients receiving up-front treatment with tamoxifen, the extension of tamoxifen 2,3 or an aromatase inhibitor to 10 years has been shown to be beneficial in reducing the ongoing risk of ...

Mechanism of Action of Aromatase Inhibitors and Tamoxifen. In contrast, aromatase inhibitors markedly suppress plasma estrogen levels in postmenopausal women by inhibiting or inactivating ...

[13] Since this 2004 study, aromatase inhibitor use and any effect on cognition remain under consideration. A 2009 ASCO Breast Cancer Symposium review of five studies evaluated the majority of ...

Aromatase inhibitors cause unwanted side effects. More and more women are choosing not to take them, but is this a good idea? The decision to walk away from taking aromatase inhibitors is a choice ...

Aromatase inhibitors, drugs which block estrogen production, are even more effective than tamoxifen in postmenopausal women, reducing this risk by a further 30%.

The German Institute for Quality and Efficiency in Health Care (IQWiG) investigated whether and what advantages drugs from the drug class of aromatase inhibitors offer compared with other breast ...

The availability of the selective aromatase inhibitors letrozole and anastrozole—currently approved as adjuvant therapy for breast cancer—have stimulated off-label use of aromatase inhibitors ...

While aromatase inhibitors usually don’t take the place of those treatments, they can offer extra help if you’re in a select group. They’re a hormone therapy used to treat some ovarian ...

Many people who’ve had breast cancer take medications – tamoxifen or aromatase inhibitors – to help prevent the cancer from coming back. Doctors prescribe them for people with “hormone ...

DEAR DR. ROACH: I am an 80-year-old female and a 25-year survivor of ovarian cancer. In the past three years, I have also had Merkel cell cancer, breast cancer, and now squamous cell cancer on my lip.

Treatment with an aromatase inhibitor, either alone or in combination with growth hormone (GH), slowed bone advancement and enhanced adult height in mid-pubertal boys with a short predicted adult ...

Aromatase inhibitors act through pure oestrogen deprivation to achieve an endocrine response in oestrogen receptor (ER)-positive breast cancer. Both experimental and clinical data now confirm that ...