According to a new study, a compound found in the blessed thistle plant accelerates the regeneration of damaged nerves, restoring motor function and touch sensation. Damaged nerve fibers (axons ...

Moreover, this expression triggers a 60-fold increase in regeneration of DRG axons in adult mice after spinal cord injury in vivo. Replacing key growth cone components, therefore, could be an ...

Scientists have been exploring ways to enable the regeneration of severed axons, with a view to developing viable treatments in the long term. Damages to the central nervous system (CNS), for ...

Injured axons instruct Schwann cells to build specialized actin spheres to break down and remove axon fragments, thereby starting the regeneration process. Damaged peripheral nerves can regenerate ...

Therefore, in-depth study of the basic biological processes that affect axon regeneration is particularly important for human health. Traditional research on axon regeneration has focused on the ...

By modifying not just the environment around spinal cord injuries, but also jumpstarting the regenerative capacities of the neurons themselves, Mark Tuszynski and colleagues at the University of ...

Some of these methods include controlled intraocular inflammation and elevation of on-comodulin and other growth factors, deletion of genes that suppress regeneration such as pten, socs3, klf4 and -9, ...

For PNS axons to regenerate and regain function, two conditions must be met: First, the injured neuron must initiate gene ...

In 30 May Nature, Tadzia GrandPre and colleagues from Yale University School of Medicine, show that antagonizing the Nogo-66 receptor (NgR) can promote axonal regeneration following spinal cord ...

“We found that glia have a metabolic switch associated with glucose metabolism that when triggered reverses inhibitory effects on growth and promotes axon regeneration,” commented Shuxin ...