Bacteria that have mutated to become particularly resistant to antibiotics often have many of these efflux pumps on their surface. To counter this defense, researchers have produced a class of ...

Scientists at the University of Cambridge have uncovered the final piece in the jigsaw revealing the structure of ‘efflux pumps’, which allow Salmonella and other disease-causing bacteria to develop ...

The paper describes the co-crystal structure of two parts of the three-part efflux pump that recognizes and removes heavy metal toxins from bacteria. A research team led by Yu -- an Iowa State ...

By modifying these “efflux pumps” to recognize the antibiotic, bacteria can eliminate the drug before it poisons them. As it turns out, some phages appear to use these same efflux pumps to ...

Yu and his research group have just described two structures and mechanisms – efflux pumps and reinforced cell walls – that certain disease-causing bacteria use to keep antibiotics away. That ...

In these two bacteria, the pumps remove sulfonamide antibiotics, allowing the bacteria to survive treatment with the drugs. Yu, who has studied other efflux pumps, said the studies of these two ...

By modifying these “efflux pumps” to recognize the antibiotic, bacteria can eliminate the drug before it poisons them. As it turns out, some phages appear to use these same efflux pumps to ...

These specific efflux pumps are able to eject the antimicrobial molecules from the bacteria, thereby conferring on them a certain level of resistance. In this experiment, the transmission of the ...

In the chemical arms race between modern medicine and quickly evolving bacteria and fungi, some researchers are now opening a new front. They’re attacking the machinery, known as efflux pumps ...

Harmful bacteria have evolved some ingenious mechanisms to resist antibiotics. One of those is the drug efflux pump—proteins that stand guard along bacterial cell membranes, identifying ...