Genomewide association studies of autoimmune diseases have mapped hundreds of susceptibility regions in the genome. However, only for a few association signals has the causal gene been identified ...

The researchers identified B cell survival factor (BAFF) as a key mediator of this neuroprotection. When examining the serum samples from human patients, the researchers found that elevated levels of ...

He says in the two years since the foundational pre-clinical work was completed, the team has shown that it's feasible to manufacture BAFF CAR T-cells for human subjects. The innovation is ...