Renibus Therapeutics® ("Renibus"), announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug ...

Studying basement membranes is challenging, however, because they are best studied in an intact animal. If you remove them from the animal, Page-McCaw said, you change their organization and their ...

Large gaps in basement membrane occur at sites of cell invasion and tissue remodelling in development and cancer. Though never followed directly in vivo, basement membrane dissolution or reduced ...

Most tumors are sheathed in a protective "basement" membrane -- a thin, pliable film that holds cancer cells in place as they grow and divide. Before spreading to other parts of the body ...

Also known as epithelial basement membrane dystrophy, map-dot-fingerprint dystrophy gets its name from the unusual appearance of the cornea during an eye examination.Map-dot-fingerprint dystrophy, ...

Drug screening in 3D cell cultures is possible with the right tools. Amid cuts to federal funding, US universities tighten budgets, forcing PhD students and early-career researchers to navigate an ...

Too much of this enzyme, matrix metalloproteinase 2 (MMP2), might be causing the disturbance to the basement membrane. An experiment using model mice with vitiligo-like depigmentation showed ...

At the early stage of breast cancer malignant cells are imprisoned by a tissue barrier called a basement membrane that stops them from disseminating into other parts of the body. This early disease ...

Too much of this enzyme, matrix metalloproteinase 2 (MMP2), might be causing the disturbance to the basement membrane. An experiment using model mice with vitiligo-like depigmentation showed ...