CHIKV can trigger long-term joint pain that mimics autoimmune diseases like rheumatoid arthritis, potentially due to ...

Chikungunya virus (CHIKV) is a mosquito-borne pathogen that has been identified in more than 110 countries around the world.

In a new study published in Science Bulletin, researchers from West China Hospital of Sichuan University present the largest human T cell reference for 68 subtypes and states, alongside STCAT, an ...

Aberrant activation of autoreactive T cells is a hallmark of autoimmune diseases. Here, by analysing CD4 T cells from patients with polymyositis and mice with experimental autoimmune myositis ...

Indeed, removal of cDCs halted the infiltration of CD8+ T cells into the brains of TE4 mice. It left unchanged the number of CD4+ T cells entering the brain. Curiously, though, it enhanced ...

A panelist discusses how CD4 counts serve as measures of immune system status that typically increase by about 200 in the ...

PT-112 monotherapy advances to phase 3 trial in metastatic castration-resistant prostate cancer after positive FDA end of ...

Metformin use in patients with HIV and type 2 diabetes who had at least 2 years of exposure to effective ART showed no significant effect on immune reconstitution.

Although T cells were detectable in the stroma surrounding the BCC, significantly fewer CD4 + and CD8 + T cells infiltrated into BCC tumor foci compared with SCCs. A survey of other immune cells ...