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A crucial mechanism in immune response: NOTCH signaling pathway plays essential role in CD8⁺ T cell differentiationThe creation of these fighting cells requires new programming of CD8 + T cells, a process known as differentiation. Previous work by the team had shown that the NOTCH signaling pathway played a ...
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Researchers gain new understanding of how immune cells respond to heat during feverStudy reveals that moderate fever temperatures (39°C) improve metabolism, proliferation, and effector function of CD4 T ... of differentiation 8 (CD8)-expressing cytotoxic T cells.
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