Regulatory T cells police the immune system, making sure that killer T cells coming back from battling pathogens transition into a resting state, but still prepared to fight if the pathogen returns.

Unlike other killer T cells, these home in on multiple cancer-associated targets at once, preventing new tumors forming for up to a year later and could lead to more effective cancer therapies.

Experimental treatment could offer a safer, cheaper alternative to CAR-T-cell therapies for disorders such as lupus.

The signals T-helper cells release instruct killer T-cells to activate, B-cells to mutate and proliferate and innate immune cells to clean up the mess. Together, all the cells and their proteins ...

In the fight against cancer, chimeric antigen receptor T cell (CAR-T) therapy has achieved notable success in treating blood cancers. However, it has been largely ineffective against solid tumors.

In the case of COVID-19, killer T cells could mean the difference between a mild infection and a severe one that requires hospital treatment, says Annika Karlsson, ...

More killer T cell quickly releases one target cell and moves onto another target. getty. Cytotoxic T cells, also known as the “killer” T cells, provide the foundation for cell-based CAR T ...

An artificial intelligence-based platform allows researchers to uncover the secrets behind adaptive immunity and killer T cells. Researchers from CellChorus (CA, USA) recently published results from a ...

[Li et al., 2018, Cell Stem Cell 23, 1–12] Immunotherapies that genetically modulate the antigenic receptors on a patient’s T cells—so-called CAR-T therapy—to seek out and destroy cancer ...

Killer T cells, as their name might imply, are not known for their mercy. When these immunological assassins happen upon a cell that’s been hijacked by a virus, their first instinct is to butcher.

Engineered killer T cells could provide long-lasting immunity against cancer. ScienceDaily. Retrieved May 30, 2025 from www.sciencedaily.com / releases / 2019 / 09 / 190924090512.htm.

CAR-redirected natural killer T cells demonstrate superior antitumor activity to CAR-T cells through multimodal CD1d-dependent mechanisms. Nature Cancer, 2024; DOI: 10.1038/s43018-024-00830-0; ...