Unlike other killer T cells, these home in on multiple cancer-associated targets at once, preventing new tumors forming for up to a year later and could lead to more effective cancer therapies.

NKT (natural killer T) cells are an innate-like lymphocyte population. They express markers associated with both T cells and NK cells. NKT cells can regulate diverse immune responses and produce ...

Alongside antibodies, the immune system produces a battalion of T cells that can target viruses. Some of these, known as killer T cells (or CD8 + T cells), seek out and destroy cells that are ...

Joost Beltman (LACDR, Leiden University) has provided novel insights in the way T-killer cells migrate towards virus-infected cells. This was accomplished by a combination of experimental research ...

The body’s defense system against infection also fights tumors, generating tumor resident stem-like T cells and killer T cells that express inhibitory receptors such as PD-1. When PD-1 binds to PD-L1 ...

Killer T cells, otherwise known as CD8+ or cytotoxic T cells, possess special molecular weapons to directly attack and destroy other cells infected by a foreign invader such as a virus.

Salk Institute scientists discovered a relationship between killer T cell exhaustion and the body’s sympathetic—“fight-or-flight”—stress response. The research showed that beta-blockers ...

Reducing stress on T cells makes them better cancer fighters Date: September 20, 2023 Source: Salk Institute Summary: Scientists discovered a relationship between the immune system's killer T ...

The gene therapy known as CAR-T uses a patient's own T-cells to target and kill malignancies. The therapy, which has been researched for decades, is now proving effective at turning sick patients ...

Research into this link revealed that immune cells called killer T cells – responsible for destroying harmful cells and pathogens – were a key player. This new research provides insight into ...

"We still don't have a standard, optimized therapy for children with cancer, especially children with brain cancer." Natural killer cells are a critical part of the human immune system, but they ...

In the fight against cancer, chimeric antigen receptor T cell (CAR-T) therapy has achieved notable success in treating blood cancers. However, it has been largely ineffective against solid tumors.