The mammalian liver has an extraordinary regenerative capacity, capable of fully restoring its mass and function after injury ...

DNA repair: A look inside the cell's 'repair café' Date: November 21, 2024 Source: Hubrecht Institute Summary: New research sheds light on how cells repair damaged DNA. For the first time, the ...

Their engineered cells can insert distinctive bits of genetic material into their DNA. As the cells divide, those genetic bits turn into distinctive bar codes. The technology is also allowing ...

They also tend to use heat to separate strands, heating the DNA to more than 150°F, a temperature a cell would never naturally reach. By contrast, in a living cell DNA lives in a very crowded ...

The researchers have studied the spatial organization of DNA that is so particular to these early developmental stages. The paper, "Antagonism between H3K27me3 and genome–lamina association ...

In the human body, billions of cells divide each day: intestinal cells are completely renewed every 1–3 days, and skin cells approximately every 2–3 weeks. During this process, DNA must be ...

But those cells have a formidable challenge. The average dividing cell must copy—perfectly—3.2 billion base pairs of DNA, about once every 24 hours. The cell’s replication machinery does an ...

Genome instability can cause numerous diseases. Cells have effective DNA repair mechanisms at their disposal. A research team has now gained new insights into the DNA damage response. Whenever ...

And although those chromosomes come from both parents, nearly all humans inherit their mitochondrial DNA (mtDNA) from their mother's egg cell. So what happens to the mtDNA in the sperm cell?