When people think of DNA, they usually think of genes, the parts that code for proteins and drive inherited traits. But there ...

With a few exceptions, eukaryotic chromosomes have a single centromere that ensures their accurate segregation during mitosis. Chromosomes that lack centromeres segregate randomly during mitosis ...

Among the many marvels of life is the cell’s ability to divide and thus enable organisms to grow and renew themselves.

When cells divide, chromosomes need to be evenly segregated. This equal distribution is important to accurately pass genetic information to the next generation. Abnormal segregation can cause cell ...

The identity of the forces that drive chromosome segregation in bacteria has long been unknown. Here, Jun and Wright describe their model in which entropy is the central driving force of ...

Pulling the genome apart: Chromosome segregation during mitosis explained Date: November 12, 2018 Source: Osaka University Summary: Researchers shed light on the protein complexes and processes ...

This fundamental finding has important implications for the process of chromosome segregation and provides new mechanisms underlying erroneous divisions in cancer cells. The research was published ...

Specialized sites on the chromosomes called kinetochores attach to spindle microtubules, and these kinetochore-microtubule attachments are necessary for proper chromosome segregation. Problems in ...

It results from errors in the segregation of chromosomes from the mother cell to the two daughter cells during mitosis, i.e., cell division, and leads to the activation of p53, ...

Numerous errors in chromosome segregation during cell division can lead to the formation of micronuclei, even if there isn’t actual mis-segregation of the chromosomes. These events are not mutually ...

Fewer chromosome segregation errors in modern human than Neanderthal neural stem cells. (IMAGE) Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG) ...

The most famous, of course, is Down’s syndrome, where there's one extra copy of one tiny chromosome.” In addition to missteps in embryo development, Shakes points out that chromosome segregation ...