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De Soto High School. 615 Main St. De Soto, Wisconsin 54624 #13,242-17,655 in National Rankings #363-462 in Wisconsin High Schools. Nearby Schools. Explore Map. Ranked School. Unranked School.
Graduation ceremonies for De Soto High School will be held in the De Soto High School new gymnasium, Friday, May 26, at 7 p.m.
Six De Soto High School athletes qualify for the 2025 WIAA Track & Field Championships at the University of Wisconsin-La Crosse.
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