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EZH2 is an enzyme that normally helps program cell behavior by controlling the expression of specific genes. Mutations in the EZH2 gene, which makes the enzyme more active, are now recognized as ...
The model of memapsin 2 and its inhibitor makes that timetable a lot more realistic, he said. "There's still a lot of basic research to do on this enzyme," Tang said.
Eckhard, U., et al. (2021) The crystal structure of a 250-kDa heterotetrameric particle explains inhibition of sheddase meprin β by endogenous fetuin-B. Proceedings of the National Academy of ...
Scientists at St Jude Children's Research Hospital published in the July 13, 2022, issue of Science Translational Medicine how they eliminated the tumor in a mouse model by inhibiting an enzyme to ...
Grapefruit juice is more than a breakfast staple — it’s a potent enzyme inhibitor that can dramatically alter how certain drugs are metabolized. This article explores how a tiny structural difference ...
The results suggest that targeted inhibition of MPO may be a promising new therapeutic approach for people with obesity and increased cardiovascular risk.
Researchers can mitigate overactive LRRK2 using MLi-2 LRRK2 kinase inhibitor, a molecule that attaches to the enzyme and decreases its activity. Pfeffer added that because the genetic mutation is not ...