Influencing their activity can control their rates of reaction. Different chemicals can influence enzyme activity. Inhibitors can be used to stop an enzyme from binding to its substrate.

Since GLP-1-based therapy is a promising novel treatment of type 2 diabetes, the strategy to inhibit the enzyme has been explored. Several DPP-4 inhibitors are in clinical development; these are ...

It was not yet clear whether it was an endopeptidase or a unique type of exopeptidase that ... as we isolated and characterized these new enzyme inhibitors. However, our synthetic expertise ...

In the brain, the enzyme ABHD6 degrades a ... obesity and metabolic disorders such as type 2 diabetes, the scientists believe. While ABHD6 drug inhibitors are being screened, it remains to be ...