Thus, candidates should be tested against a panel of receptors at the time of antibody engineering. ACROBiosystems provides an extensive collection of recombinant Fc receptor proteins, which ...

Previous studies established defective Fc receptor mediated clearance in patients with systemic lupus erythematosis (SLE), a disorder associated with circulating immune complexes (CIC).

Generalized myasthenia gravis (gMG) affects most patients through a handful of well-characterized neuromuscular junction ...

The Dutch biotech company said the product was the first and only neonatal Fc receptor blocker approved to treat the condition. The product is co-formulated with Halozyme Therapeutics’ (HALO ...

The binding between a biosimilar and its target antigen (and Fc receptors) is regarded as a key indicator of its efficacy. ACROBiosystems has designed high-quality target antigen proteins and Fc ...

Opens in a new tab or window Recently approved treatments for generalized myasthenia gravis (gMG), including complement and neonatal Fc receptor (FcRn) inhibitors, offer a new treatment paradigm ...

Argenx (ARGX) announced clinical trial and real-world data for Vyvgart and Vyvgart Hytrulo will be presented at the American Academy of ...

Concentration-dependent cleavage of IgE B cell receptor. Concentration-dependent reduction of expression of the high-affinity IgE Fc receptor, on bone marrow-derived mast cells from humanized mice.

Proteintech has designed recombinant antibodies featuring the company's FcZero backbone, engineered to silence the Fc domain ...