Patients with predominantly cranial vs isolated extracranial GCA phenotypes present with different patterns of arterial involvement on 18F-FDG PET-CT scans.

Giant cell arteritis (GCA) and polymyalgia rheumatica ... is CD4 + T cells and the key cytokines are IFN-γ (implicated in granuloma formation) and IL-6 (key to the systemic response).

including central giant cell granuloma (CGCG) and central giant cell reparative granuloma (CGCRG). While generally benign, these lesions can exhibit aggressive behavior, leading to significant ...

Giant cell arteritis, or GCA, is a condition where arteries in the head and neck become inflamed. It is called ‘giant cell’ because abnormally large cells accumulate in the artery walls.

Peripheral Giant Cell Granuloma (PGCG) is a benign oral lesion that often appears in the gingiva and can be associated with dental implants. This condition is characterized by a proliferation of ...

The microscopical appearances are those of a granulomatous or giant-cell aortitis or mesaortitis, usually found in association with a temporal or cranial arteritis, 9,10 and closely corresponding ...

Giant cell arteritis (GCA) is a medical emergency ... Epitheloid cells in the granuloma cause injury to the arterial wall by secreting matrix metalloproteinases and reactive oxygen and nitrogen ...