“A high MCHC is pretty uncommon, and that's seen in some red blood cell disorders,” Gallagher says. For instance, it can be caused by sickle cell disease or hereditary spherocytosis.

When someone inherits two mutant copies of the hemoglobin gene, the abnormal form of the hemoglobin protein causes the red blood cells to lose oxygen and warp into a sickle shape during periods of ...

Sickle cell disease (SCD) is a group of inherited blood disorders resulting from a mutation in the hemoglobin protein in red blood cells. This mutation changes the shape of the blood cells from round, ...

Hydroxyurea remains effective long-term in reducing emergency department visits and hospital days for children living with sickle cell disease (SCD), according to new research published in Blood ...

A smear of this patient's blood showed that "the shape of the red cells was very irregular, but what especially attracted attention was the large number of thin, elongated, sickle-shaped and ...

Sickle cell disease affects only adult hemoglobin, causing it to clump and distort red blood cells into a sickle shape. Preserving fetal hemoglobin after birth at levels above 8% through gene ...

Sickle cell is the most common genetic blood ... descent causes intense pain as it produces unusually shaped red blood cells that can block blood vessels which can be life-threatening.

This month, 21-year-old Sebastien Beauzile became the first man in New York history to be cured of sickle cell anemia ... to create normal red blood cells. Since receiving the treatment in ...

Sickle cell is a blood disorder where the body creates mutated red blood cell proteins. It often leads to pain, anemia and other issues. The National Institute of Health says it touches more than ...