Heparin-induced thrombocytopenia (HIT) can be a serious complication of unfractionated heparin therapy. There are two types of HIT: Type I HIT: This form is non-immune mediated. Thrombocytopenia ...

HIT is tricky to diagnose because thrombocytopenia (low blood platelets) can have various causes and is common in hospitalized patients. Only 1%–5% of patients who take heparin develop HIT, but ...

A brief overview of the pathophysiology, diagnosis, and treatment of heparin-induced thrombocytopenia (HIT) is discussed. Following any exposure to unfractionated heparin or low-molecular-weight ...

DVT denotes deep-vein thrombosis, HIT heparin-induced thrombocytopenia, IVIG intravenous immune globulin, PE pulmonary embolism, PF4 platelet factor 4, SVT superficial-vein thrombosis, and VITT ...

INTERVENTION: None. MEASUREMENTS: VTE, major bleeding or heparin-induced thrombocytopenia, mortality, and cost. RESULTS: Of 32,104 patients who received prophylaxis, 55% received LMWH and the ...

Severe side effects associated with both medications include: Hemorrhage (severe bleeding) Heparin-induced thrombocytopenia ...

has a much longer half-life and less commonly causes heparin-induced thrombocytopenia (HIT). Monitoring drug activity is not usually necessary for LMWH unlike unfractionated heparin which requires ...

Heparins are a group of related compounds comprised of a mixture of glycosaminoglycans usually derived from porcine intestine. They exert their effect by binding to antithrombin, which inhibits ...