In her lab at Washington University in St. Louis, endocrinologist Jing Hughes studies a peculiar structure that sticks out of the surfaces of human pancreatic islet cells: the primary cilium. The ...

These solitary and apparently nonfunctional cilia are far more widespread ... understanding of both fundamental cell sensory processes and a variety of human disorders. In general, the primary ...

Tiny hairlike structures on pancreatic cells have long been considered static sensors ... Hughes and colleagues began their investigation by imaging primary cilia in human and mouse pancreatic islets.

A growing number of new studies have found that, at least for some cells, death isn’t the end, but the beginning of something ...

Researchers from the University of New Hampshire looked at the developmental process of the cerebral cortex—the outermost ...

but this requires that all cilia in a tissue orient the same way. Earlier studies indicated that both planar cell polarity (PCP) signalling and cilia-generated fluid flows could influence ciliary ...

The goblet cells secrete mucin proteins in a matrix composed of water, complex sugars, salts which form the mucus. This matrix is distributed evenly on the surface of the epithelium by the ...

Cilia are the hairlike structures on the surface of cells. They move in conjunction with mucus to repel and expel foreign bodies. To test their hypothesis, the team cultured human airway ...