Here the authors measure metabolic changes in human monocytes from different aged donors and find enhanced oxidative phosphorylation fueling myeloid differentiation in neonates which contrasts ...

Surface-bound MIF induced arrest of primary human monocytes through CXCR2 and triggered the arrest of primary human effector T cells via CXCR4. Furthermore, CD74 (a MIF-binding protein ...

Non-classical monocytes, for one, patrol blood vessels for potential threats and remove damaged cells, debris and pathogens to help maintain the body’s immune response. Researchers studied the ...

Introduction of the variants into healthy cells abolished CCR2 protein expression, and the patients’ own monocytes lacked the receptor. Neehus’s collaborators next set up an in vitro cell migration ...