X-ray and nuclear magnetic resonance studies have also revealed conformational changes that occur on IgE binding to its high-affinity receptor FcεRI (high-affinity Fc receptor for IgE ...

Concentration-dependent cleavage of IgE B cell receptor. Concentration-dependent reduction of expression of the high-affinity IgE Fc receptor, on bone marrow-derived mast cells from humanized mice.

In vitro, omalizumab and human IgE form several immune complexes that vary in size as the 2 components' molar ratios are changed. [29] The largest complex, a stable cyclical hexameric structure ...

Data is presented at the 2025 American Academy of Allergy, Asthma and Immunology (AAAAI) / World Allergy Organization (WAO) Joint Congress "We believe we are at the forefront of an emerging field ...