Joost Beltman (LACDR, Leiden University) has provided novel insights in the way T-killer cells migrate towards virus-infected cells. This was accomplished by a combination of experimental research ...

Research into this link revealed that immune cells called killer T cells – responsible for destroying harmful cells and pathogens – were a key player. This new research provides insight into ...

T-cell receptor and have a potent immunoregulatory function. Because mouse models of allergic asthma indicate that natural killer T cells are required for the development of allergen-induced ...

More information: Xin Zhou et al, CAR-redirected natural killer T cells demonstrate superior antitumor activity to CAR-T cells through multimodal CD1d-dependent mechanisms, Nature Cancer (2024 ...

Alongside antibodies, the immune system produces a battalion of T cells that can target viruses. Some of these, known as killer T cells (or CD8 + T cells), seek out and destroy cells that are ...

The gene therapy known as CAR-T uses a patient's own T-cells to target and kill malignancies. The therapy, which has been researched for decades, is now proving effective at turning sick patients ...

CART therapy involves removing T-cells from the blood of patients and reprogramming those cells so they can recognize and destroy cancer. Novartis drummed up excitement for the technology back in ...

Cancer-specific killer T cells created from induced pluripotent stem cells (iPSC) Date: January 3, 2013 Source: RIKEN Summary: Researchers in Japan report today that they have succeeded for the ...

Now, a newly published study by UNC Lineberger Comprehensive Cancer Center researchers demonstrates that a different immunotherapy approach utilizing natural killer T (NKT) cells produced ...

These drugs each target a distinct checkpoint protein on frontline troops, aptly named killer T cells. Nearly 58 percent of those getting both drugs showed tumor shrinkage of 30 percent or more in ...

It is the first living cell therapy that can navigate through the body to a specific organ, addressing what has been a major limitation of CAR-T cancer therapies until now. The technology worked in ...

A study demonstrates that a different immunotherapy approach utilizing natural killer T cells produced significant antitumor activity in preclinical models of solid tumors. In the fight against ...