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The Last of Us introduced the dangerous infected in the very first episode of the video game adaptation, but those "Runners" proved to be nothing in comparison to the Clickers that were introduced ...
HBO’s The Last of Us series is a pretty darn faithful adaptation ... and you become what’s called a ‘Clicker,’ because now these infected use echolocation to find their way.” ...
In The Last of Us Season 2 Episode 5, Ellie discovers a new way for people to get infected: spores, and they’re horrifying.