Aminoglycoside antibiotics (AGAs ... along with the most common bacterial resistance mechanisms, are outlined. Finally, the recent development situation and possibility of new AGAs in the ...

Bacterial antibiotic resistance mechanisms include efflux ... of the mRNA–tRNA complex through the ribosome (such as the aminoglycosides hygromycin B, neomycin, pactamycin and spectinomycin ...

Aminoglycosides are bacteriostatic; they slow down the growth and reproduction of bacteria without killing them. These antibiotics inhibit the synthesis of proteins by binding to the 30S bacterial ...

Nucleotidyltransferases exhibit similar enzymatic activity for the modification of aminoglycosides ... molecular mechanisms ...

These experiments indicated that the single aberrant plant protein killed cells by the same mechanism as the complex mixture of aberrant proteins induced by aminoglycoside antibiotics. But the ...

developed to circumvent most existing aminoglycoside resistance mechanisms. Professor Joakim Larsson, senior author of the study and director of the Centre for Antibiotic Resistance Research at ...

Choosing the appropriate antibiotics to treat bacterial ... Two primary resistance mechanisms—aminoglycoside enzymatic modification and 16S rRNA methylation—were assessed, and the prevalence ...

Although use of aminoglycosides is associated with low incidence of antibiotic resistance ... However, the underlying mechanisms responsible for the hearing loss were not clearly known until ...

Staphylococcus strains resistant to aminoglycosides and β-lactams ... However, the presence of these mechanisms in isolated, pre-antibiotic-era environments raises questions about how resistance ...