Neuregulin (NRG) is a crucial regulator of oligodendrocyte development, strongly promoting both the proliferation of oligodendrocyte precursor cells and the survival and maturation of ...

Study: Pervasive environmental chemicals impair oligodendrocyte development.Image Credit: Lightspring / Shutterstock. Background . Human exposure to environmental chemicals, especially during the ...

But oligodendrocyte-containing brain spheroids could also prove useful in studying demyelination disorders, such as multiple sclerosis and cerebral palsy—and even some psychiatric conditions not ...

While most oligodendrocyte progenitor cells differentiate into oligodendrocytes during the development of the central nervous system at a young age, some remain as progenitor cells until adulthood ...

However, when mTOR is inhibited by Rapamycin in the early stages of oligodendrocyte development, the oligodendrocytes are still able to fully differentiate. Tribbles Homolog 3 (Trib3) is a pseudo ...

Deficiency in the omega-3 lysolipid transporter Mfsd2a leads to aberrant oligodendrocyte lineage development and hypomyelination Article Publication Date 27-Apr-2023 ...

Directed differentiation approach prompted mouse EpiSCs to convert into functional oligodendrocyte progenitors. A technique for generating pure populations of mouse oligodendrocyte progenitor ...

During normal development of the rodent brain, myelin oligodendrocyte glycoprotein is considered a marker of mature or myelinating oligodendrocytes 28 and has not been detected in premyelinating ...

Lineage Announces Notice of Allowance of Two Patents Covering Processes for Manufacturing Allogeneic Oligodendrocyte Progenitor and Retinal Pigmented Epithelium Cells October 10, 2022 08:00 AM ...

The research team in National Institute for Physiological Sciences (Okazaki, Aichi, Japan) developed a novel method for labeling a single oligodendrocyte and revealed characteristics of selective ...