Oligodendrocyte morphology. Oligodendrocytes grown in media containing thyroid hormone labeled for oligodendrocyte markers at day 3 in vitro.

Figure 3. Characterization of ioOligodendrocyte-like cells show oligodendrocyte morphology in culture and presence of early and late-stage oligodendrocyte-specific markers.

These cells may be identified by their A2B5 + PSA-NCAM - phenotype (positive for the early oligodendrocyte marker A2B5 and negative for the polysialylated neural cell adhesion molecule).

Oligodendrocyte differentiation from oligodendrocyte precursor cells (OPCs) follows a temporally and spatially well-orchestrated path, which can be traced by consecutive marker acquisition ...

Optimizing iPSC differentiation significantly improves in vitro Alzheimer's disease models, leading to more accurate and reliable research outcomes.

The research team in National Institute for Physiological Sciences (Okazaki, Aichi, Japan) developed a novel method for labeling a single oligodendrocyte and revealed characteristics of selective ...

While oligodendrocyte generation normally dwindles after the first several weeks of life, the mutants were still turning out abundant newborn oligodendrocytes at two months of age, and the ...

Lineage Announces Notice of Allowance of Two Patents Covering Processes for Manufacturing Allogeneic Oligodendrocyte Progenitor and Retinal Pigmented Epithelium Cells ...

In a new study, researchers with the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have identified a distinct histone tag in adult oligodendrocyte progenitor cells (OPCs ...

However, when mTOR is inhibited by Rapamycin in the early stages of oligodendrocyte development, the oligodendrocytes are still able to fully differentiate. Tribbles Homolog 3 (Trib3) is a pseudo ...