Therefore, we performed spinal immunohistochemistry for Olig2, a well-characterized marker protein for oligodendrocyte precursors as well as mature oligodendrocytes 10 (typical examples in Fig. 4d ...

OPC morphology. OPCs grown in media containing bFGF/PDGF labeled for oligodendrocyte markers at day 3 in vitro.OPCs labeled positively for NG2 (A), A2B5 (B), GalC (C) and MBP (D).

Figure 3. Characterization of ioOligodendrocyte-like cells show oligodendrocyte morphology in culture and presence of early and late-stage oligodendrocyte-specific markers.

These cells may be identified by their A2B5 + PSA-NCAM-phenotype (positive for the early oligodendrocyte marker A2B5 and negative for the polysialylated neural cell adhesion molecule).

Cells were stained for DAPI, MBP as myelin/oligodendrocyte marker, beta-III tubulin or NF-200 to stain neuronal axons, GFAP as astrocyte marker, and Iba1 microglia marker.

They observed that YFP-positive cell numbers in the spinal cord quadrupled during demyelination, and more than 90 percent of the YFP cells were of oligodendrocyte lineage. They also observed that ...

During normal development of the rodent brain, myelin oligodendrocyte glycoprotein is considered a marker of mature or myelinating oligodendrocytes 28 and has not been detected in premyelinating ...

This cycle of oligodendrocyte degeneration and renewal is responsible for the relapses and remissions of multiple sclerosis, noted senior author Dwight Bergles. He and Rothstein previously reported ...

The research team in National Institute for Physiological Sciences (Okazaki, Aichi, Japan) developed a novel method for labeling a single oligodendrocyte and revealed characteristics of selective ...

OPC1 is an oligodendrocyte progenitor cell (OPC) transplant therapy designed to provide clinically meaningful improvements to motor recovery in individuals with acute spinal cord injuries (SCI).