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Whakaihu Waka researchers have been part of two studies in the battle against drug resistant strains of Mycobacterium ...
When the antibiotic bedaquiline was introduced in 2012, it was the first new tuberculosis drug in over 40 years. Bedaquiline ...
Called "Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis," their work involves characterizing the enzymes using the UK's national synchrotron ...
And now, in a paper published online by the journal Nucleic Acids Research, a research team led by Yu describes the structure of a regulator that controls the expression of the multidrug efflux pump ...
A number of compounds prepared by this method were shown to possess impressive activity against Mycobacterium tuberculosis, extremely low toxicity and therefore high therapeutic indexes, as well as ...