Vein irritation can occur during PICC insertion or when the vessel is too small to accommodate the diameter of the PICC. A PICC that is too large will abrade the intima of the vein into which it ...

Several factors contraindicate PICC placement: lack of peripheral access, venous thrombosis, and end-stage renal disease. In addition, PICCs should not be used for frequent intermittent access or ...