Preview the May 16 matchup between the Philadelphia Phillies and Pittsburgh Pirates with odds over/under, game spread, betting lines and more.

The St. Louis Cardinals (23-19) and Philadelphia Phillies (24-17) clash in a Wednesday doubleheader at Citizens Bank Park. Game 2 is set for a 6:15 p.m. ET start. Let's analyze BetMGM Sportsbook's MLB odds around the Cardinals vs. Phillies odds and make our expert MLB picks and predictions for the best bets.

Its Wednesday, May 14 and the Cardinals (23-19) are in Philadelphia to take on the Phillies (24-17). Erick Fedde is slated to take the mound for St. Louis against Jesus Luzardo for Philadelphia.