In her lab at Washington University in St. Louis, endocrinologist Jing Hughes studies a peculiar structure that sticks out of the surfaces of human pancreatic islet cells: the primary cilium. The ...

In healthy cells, primary cilia are essential for growth and repair ... "When we started studying this structure, we expected cancer cells not to have cilia, because the presence of cilia had ...

“There’s a big disconnect there.” Most cells in the body — including those in the brain — possess what’s called a primary cilium, made up of lipid molecules and proteins. The functions ...

A change in shape to a particular structure of neurons was found to ... accumulates in the antennae-like structures known as primary cilia in several groups of neurons in the hypothalamus region ...

"When we started studying this structure, we expected cancer cells ... More information: Rebecca Collinson et al, Primary cilia and cancer: a tale of many faces, Oncogene (2025).