The transcription of a gene is controlled by a so-called promoter region, which is located directly before the start of the gene. More detailed investigations in recent years have indicated that ...

In addition, regulatory sites on prokaryotic DNA are typically located close to transcription promoter sites — and this plays an important part in gene expression. For an example of how this ...

Not all genes are active at all times. DNA methylation is one of several epigenetic mechanisms that cells use to control gene expression. This straightforward experiment demonstrated that it was ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

The numbers of the principal regulatory elements present in insulin promoters are listed. Given the complexity and uncertainty of predicting the transcriptional outcome of mutations within ...

New analyses find that divergent transcription, in which one promoter directs the expression of two adjacent genes oriented in opposite directions, is conserved across all domains of life. Jack is a ...

Synthetic plasmids often exhibit unpredictable gene expression behaviors that have not been completely understood. Intra-genetic elements like promoters and ribosomal binding sites have long been ...

The availability of insulin genes from a wider range of species will ... and appreciation of the subtle and sophisticated insulin promoter.