Promoter sequences are DNA sequences that define where transcription of a gene by RNA polymerase begins. Promoter sequences are typically located directly upstream or at the 5' end of the ...

The transcription of a gene is controlled by a so-called promoter region, which is located directly before the start of the gene. More detailed investigations in recent years have indicated that ...

In addition, regulatory sites on prokaryotic DNA are typically located close to transcription promoter sites — and this plays an important part in gene expression. For an example of how this ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

The availability of insulin genes from a wider range of species will ... and appreciation of the subtle and sophisticated insulin promoter.

New analyses find that divergent transcription, in which one promoter directs the expression of two adjacent genes oriented in opposite directions, is conserved across all domains of life. Jack is a ...

MIT engineers have designed a new method to improve the precision of gene therapy treatments by using gene circuits that ...

Synthetic plasmids often exhibit unpredictable gene expression behaviors that have not been completely understood. Intra-genetic elements like promoters and ribosomal binding sites have long been ...

The numbers of the principal regulatory elements present in insulin promoters are listed. Given the complexity and uncertainty of predicting the transcriptional outcome of mutations within ...