A new study suggests that never-seen-before stem cells in the human retina can restore vision in mice with a common eye ...

Transplantation of retinal organoid sheets offers hope to patients afflicted with retinal degenerative diseases.

Base editing corrected a mutation that causes macular degeneration, highlighting the potential of gene therapy to treat ...

Image Credit: Newcells Biotech A two-dimensional in vitro model of retinal pigment epithelial cells derived from human induced pluripotent stem cells that replicate the phagocytosis of outer ...

We used patient iPSC-derived retinal pigment epithelium (RPE ... therapy is now in phase I/II clinical trials for CEP290-LCA. Cell replacement therapy offers a therapeutic approach for patients ...

A cell-based subretinal implant shows promise in the treatment of geographic atrophy, achieving the unprecedented milestone ...

A treatment called retinal pigment epithelial (RPE) cell transplantation, has shown early success in clinical trials. By replacing damaged retinal cells with healthy ones, researchers hope to slow or ...

Shihabeddin et al utilized single-cell RNA-Seq analysis of adult P23H zebrafish animals to identify transcription factors (e2fs, Prdm1a, Sp1) expressed selectively in neural progenitors and immature ...

Once inside retinal cells, the functional RPE65 protein enables the regeneration of 11-cis-retinal, which improves light detection and restores vision. In healthy individuals, RPE65 in retinal pigment ...

Lineage’s neuroscience focused pipeline currently includes: (i) OpRegen ®, a retinal pigment epithelial cell therapy in Phase 2a development under a worldwide collaboration with Roche and ...