Researchers at Children's Hospital of Philadelphia (CHOP) have identified genes responsible for hematopoietic stem cell (HSC) regeneration via the assembly of the ribosome, the protein factories in ...

Before a cut axon can attempt to grow, it first has to assemble a new growth cone at its tip. The mechanism leading to the assembly of a new growth cone includes the following events: membrane ...

According to a new study, a compound found in the blessed thistle plant accelerates the regeneration of damaged nerves, restoring motor function and touch sensation. Damaged nerve fibers (axons ...

"We are deciphering the mechanism of axon regeneration piece by piece," says ... Ribosomal protein genes are needed for making ribosomes, which are tiny factories in the cell responsible for ...

In 30 May Nature, Tadzia GrandPre and colleagues from Yale University School of Medicine, show that antagonizing the Nogo-66 receptor (NgR) can promote axonal regeneration following spinal cord ...

Axonal regeneration in the adult central nervous system is extremely limited after injury. As a consequence, there is typically little functional recovery after spinal cord injury, traumatic brain ...

Therefore, in-depth study of the basic biological processes that affect axon regeneration is particularly important for human health. Traditional research on axon regeneration has focused on the ...

For PNS axons to regenerate and regain function, two conditions must be met: First, the injured neuron must initiate gene ...

Analysis of the presence of inflammatory proteins during the repair process suggested that PDGF-BB administration not only promotes axon regeneration, but also reduces inflammation. RNA sequencing ...

The paper Y. Cho et al., “Injury-induced HDAC5 nuclear export is essential for axon regeneration,” Cell, 155:894–908, 2013. To regenerate after injury, a nerve cell must turn on gene programs that ...