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Once exposed to this protein, results showed, pericytes change shape and inhibit the production of some molecules while secreting others, creating "cellular bridges" that support regeneration of axons ...
The paper Y. Cho et al., “Injury-induced HDAC5 nuclear export is essential for axon regeneration,” Cell, 155:894–908, 2013. To regenerate after injury, a nerve cell must turn on gene programs that ...
For PNS axons to regenerate and regain function, two conditions must be met: First, the injured neuron must initiate gene ...
Analysis of the presence of inflammatory proteins during the repair process suggested that PDGF-BB administration not only promotes axon regeneration, but also reduces inflammation. RNA sequencing ...