Discovery of innate immune receptor "brake" Siglec-E offers a novel therapeutic target to prevent organ transplant rejection ...

Northwestern Medicine investigators have discovered new intracellular mechanisms that help specialized immune cells adapt and ...

A key enzyme and its molecular pathway are critical to keeping certain immune cells active and away from "exhaustion," ...

Researchers have developed an innovative dual-receptor T-cell therapy that promises safer and more effective cancer ...

WEHI scientists have uncovered a promising new way to enhance the effectiveness of vaccines by tapping into the potential of a specific type of immune cell, opening the door to long-lasting vaccines ...

IO Biotech's first-in-class vaccine performs double duty, killing cancer cells and enhancing the tumor microenvironment. A ...

A next-generation, anti-CD19 enhanced (or "armored") CAR T-cell product showed promising efficacy and safety in a phase I ...

When Treg cells are produced, they are trained to recognize specific peptides, including self-peptides from the body. When dendritic cells present a self-peptide, the peacekeeper Treg cells trained to ...

From a meeting that celebrates basic research and being "first," a look at 3 data sets on therapies that would break new ...