Without those enzymes, the lysosome isn't able to break down these ... Without GAA, glycogen builds up in muscle cells and other cells. Tay-Sachs disease. This is caused by a lack of the enzyme ...

Tay-Sachs and Hurler syndromes – associated with enzyme deficiencies within structures called lysosomes, which break down large molecules in most cells. In each of the diseases, babies typically ...

The new approach will allow researchers to see lysosomes at work and to piece together their role in diseases such as cancer and Tay-Sachs, a genetic disorder from which children typically die by ...