Two-photon microscope image of the germinal center inside a lymph node, showing tingible body macrophages (red). [Garvan] During an immune response, a massive number of B cells are made inside the ...

Even its name is a testament to how enigmatic the tingible macrophage has been. Tingible, which means stainable, certainly gives no clues to its functions – but was, at least, one thing that was known ...

For almost 140 years, the origin and behavior of an enigmatic cell type inside lymph nodes, called a tingible body macrophage, has remained a mystery. Now scientists have tracked the cell's ...

For almost 140 years, the origin and behaviour of an enigmatic cell type inside lymph nodes, called a tingible body macrophage, has remained a mystery. Now, for the first time, scientists at the ...

Tingible, which means stainable, certainly gives no clues to its functions – but was, at least, one thing that was known about the cells. Now, scientists at the Garvan Institute of Medical Research ...

More information: Neta Gurwicz et al, Tingible body macrophages arise from lymph node–resident precursors and uptake B cells by dendrites, Journal of Experimental Medicine (2023). DOI: 10.1084 ...

follicular dendritic cells and tingible body macrophages — or in the supply of antigen. As the progeny of germinal centre B cells includes long-lived plasma cells, selection of autoreactive B ...

Embryonic macrophages regulate the number of stem cells. Although they have a similar morphology (external characteristics), these macrophages differ significantly in terms of their function.