Carbonell, W. S., Ansorge, O., Sibson, N. & Muschel, R. The vascular basement membrane as “soil” in brain metastasis. PLoS One 4, e5857 (2009). An assumption ...

Cell loss is associated with the thickening of the vascular basement membrane in the retinal blood vessels, a characteristic microscopic feature of DR. An enzyme called lysyl oxidase (LOX ...

Dr. Reiner Wimmer, First Author One disease feature of diabetes is the abnormal thickening of the vascular basement membrane, which impairs the supply of oxygen and nutrients to cells and tissues.

Diabetic blood vessel changes in patients and human vascular organoids. The basement membrane (green) around the blood vessels (red) is massively enlarged in diabetic patients (white arrows). The ...

Integrins couple endothelial cells to the underlying vascular basement membrane, thereby participating in vascular growth and vessel stability. Recent studies by our group have identified signaling ...

"Surprisingly, we could observe a massive expansion of the basement membrane in the vascular organoids," said Wimmer. "This typical thickening of the basement membrane is strikingly similar to the ...