In many genetic diseases, a small error in the DNA code can have devastating effects. These errors, called nonsense mutations ...

Aminoglycosides are very powerful antibiotics, and their side effects can be severe. The Food and Drug Administration (FDA) has issued black-box warnings for aminoglycosides taken orally or ...

An international team of researchers, including scientists of the University of Groningen, has now demonstrated how the antimalarial drug mefloquine can enhance the effect of aminoglycosides, another ...

Neomycin belongs to a class of drugs called aminoglycosides. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

An international team of researchers, including scientists of the University of Groningen, have now demonstrated how the antimalarial drug mefloquine can enhance the effect of aminoglycosides ...

This makes it difficult for researchers to assess how common it is as a side effect of aminoglycosides. Chemotherapy drugs target and kill different types of cancer cells. The type of chemotherapy ...

Preliminary results using a class of drugs called aminoglycosides, commonly used as antibiotics, had had promising effects in vitro and in cell culture. A new approach to treating vision loss ...

This knowledge will help to guide the physician toward choosing an alternative drug rather than aminoglycosides, or to closely monitor the dosage-level owing to the increased risk of hearing ...

Of note, no trials have assessed clinical outcomes; therefore, it is unclear whether the application of these pharmacokinetic differences in aminoglycosides to dosing in patients with SCI ...