The dome has been a-rockin'. Reality may come a-knockin. The Dome at America's Center, the St. Louis landmark that hosted the ...

St. Louis' average homicide rate remained well above most of the nation's largest cities during a national rise in killings, ...

I-55 in St. Louis is undergoing lane shifts due to MoDOT's bridge refurbishment project, affecting traffic patterns.

Several small business owners gathered Thursday in St. Louis to speak out against a new wave of U.S. tariffs they say are ...

A suspect was taken to the hospital after an officer-involved shooting in the City of St. Louis. According to police, shots ...

A St. Louis nonprofit executive, Cymone McClellan, has pleaded guilty to defrauding over $2 million from a fund intended to ...

The deadly May 16 tornado has greatly impacted families in north St. Louis, as well as the daycare centers where they send ...

St. Louis is what senior research meteorologist Harold Brooks calls “rich with tornado history.” ...

The new "gossip commitment" was leaked to 5 On Your Side, showing the crackdown on media leaks isn't exactly working.

The Springfield Cardinals, the Double-A affiliate of the St. Louis Cardinals, were part of some unique history on Wednesday night, as noted by the organization ...