African sleeping sickness, caused by the parasite Trypanosoma brucei, is transmitted by the tsetse fly and is fatal if left untreated. New research reveals a method to manipulate trypanosomes in ...

African trypanosomiasis, or sleeping sickness, is a disease caused by a parasite and spread by the tsetse fly in sub-Saharan Africa. Infections begin with mild to moderate symptoms like fever and ...

The popular name of African trypanosomiasis—sleeping sickness—underestimates the disease's severity. Tsetse flies transmit two subspecies of the pathogen Trypanosoma ...

Whatever happened to a $1.8 millon grant Cleveland State University was awarded to research African sleeping sickness? The research group from CSU's College of Sciences and Health Professions is ...

Flagellar or ciliary motility is important for cytokinesis in some protists. In the example of the African trypanosome ... for drug design against sleeping sickness, a tropical disease of Sub ...

The researchers have compiled a high-precision inventory of the membrane proteins of cell organelles of the African sleeping sickness pathogen. "Some of these proteins contain components that are ...

Paul Capewell receives funding from The Wellcome Trust. Annette MacLeod does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this ...

New diagnostic tools are being tested that would quickly indicate whether a person has African sleeping sickness. Current methods of diagnosis are slow and cumbersome and delay life-saving treatment.

PaxMedica is expecting to file an NDA with the U.S. Food and Drug Administration (FDA) for the use of PAX-101 to treat Stage 1 African Sleeping Sickness (also known as Human African ...

Cyanotriazole compounds are fast-acting topoisomerase II poisons that can selectively and rapidly kill trypanosome parasites that cause Chagas disease and African sleeping sickness, according to a ...

(HAT), commonly referred to as African Sleeping Sickness, has recently received treatment with PAX-101, an intravenous form of Suramin, and is recovering at home. The Rhodesiense strain of Human ...