News

Ancient ambidextrous protein breaks the rules of molecular handedness
A study has found that an ancient protein motif that binds to nucleic acids is functionally "ambidextrous." This means that ...
Mirage News2d
From Sequence To Structure: Fast Track For RNA Modeling
In Biology 101, we learn that RNA is a single, ribbon-like strand of base pairs that is copied from our DNA then read like a recipe to build a ...
IndiaPost NewsPaper3d
TB-500 Peptide in Research and Scientific Domains
TB-500, a synthetic version of a naturally occurring peptide called Thymosin Beta-4 (Tβ4), has gained significant attention ...
eLife3d
Conserved and Unique Features of Terminal Telomeric Sequences in ALT-Positive Cancer Cells
The authors confirm that telomeres in telomerase-positive cells terminate with 5'-ATC in a Pot1-dependent manner, and demonstrate that this principle holds true in telomerase-negative ALT cells as ...
IEEE28d
PKAN: Leveraging Kolmogorov-Arnold Networks and Multi-modal Learning for Peptide Prediction with Advanced Language Models
Their primary structure can be depicted either as an amino acid sequence or as a chemical molecules consisting of atoms and chemical bonds. Large language models (LLMs) hold the potential to ...
C&EN1mon
Role of Electron Spin, Chirality, and Charge Dynamics in Promoting the Persistence of Nascent Nucleic Acid–Peptide Complexes
Department of Chemical and Biological Physics, Weizmann Institute of Science, Rehovot 76100, Israel ...
C&EN1mon
Biomimetic Total Synthesis and Paired Omics Identify an Intermolecular Diels–Alder Reaction as the Key Step in Lugdunomycin Biosynthesis
Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 7, Groningen 9747 AG, The Netherlands Zernike Institute for Advanced Materials, University of Groningen, Nijenborgh 4, Groningen ...
technologynetworks1mon
Essential Amino Acids: Chart, Abbreviations and Structure
Amino acids are the building blocks that form polypeptides and ultimately proteins. Consequently, they are fundamental components of our bodies and vital for physiological functions such as protein ...
eLife1mon
Simultaneous polyclonal antibody sequencing and epitope mapping by cryo electron microscopy and mass spectrometry – a perspective
We evaluate the performance of the deep-learning tool ModelAngelo in determining de novo antibody sequences directly from reconstructed ... down to the pairwise contacts between specific amino acid ...