Cilia are important for regulating cellular processes, but because of their small size and number, it has been difficult for scientists to explore cilia in brain cells with traditional techniques ...

By reexamining 3D images used to map the connections between brain cells, researchers are uncovering new information about a small, elusive, and often overlooked cellular appendage.

2007; Al Omran et al., 2017). Cilia-and flagella-associated protein 221 (CFAP221), also known as primary ciliary dyskinesia protein 1 (PCDP1), is a CP protein that regulates ependymal ciliary motility ...

and their roles in each step of cilia formation. Using CRISPR-Cas9 knockouts, we show that the order of the recruitment of the distal appendage proteins is highly interconnected and a more complex ...

1 Primary Ciliary Dyskinesia Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UK Background Quality of life (QOL)-primary ciliary dyskinesia (PCD) is the first ...

Ciliated edges were observed by microscopy and the deviation of cilia during their recovery stroke relative to the path travelled during their power stroke was measured. Beat frequency measurements ...