However, while AI and other non-animal research methods—such as computational models, advanced cell cultures, and organ-on-chip technologies, represent exciting progress, it is important to ...

Instead of using animal models or other organisms such as yeast, iPS cell technology allows human stem cells to be created from people with specific genetic mutations. Because the iPS cells contain a ...

FDA Modernization Act 2.0: transitioning beyond animal models with human cells, organoids, and AI/ML-based approaches. The Journal of Clinical Investigation, 133(21), e175824.